Distance from Knoxville, TN to San Mateo, CA

Driving directions and distance from Knoxville, TN to San Mateo, CA. See miles, drive time, and estimated gas cost for the trip.

By road
2,642 miles
Straight line
2,114 miles
Drive time
44 hr 2 min
Gas (25 MPG)
105.7 gal

Trip cost calculator

Trip details

From Knoxville, Tennessee (population: 183,270)
To San Mateo, California (population: 101,128)
Driving distance 2,642 miles
Straight-line (as the crow flies) 2,114 miles
Estimated drive time 44 hr 2 min (avg 60 mph)
Gas needed at 25 MPG ~ 105.7 gallons
Gas needed at 30 MPG ~ 88.1 gallons
Knoxville coordinates 35.9606°, -83.9207°
San Mateo coordinates 37.5630°, -122.3255°

Frequently asked questions

How many miles is it from Knoxville, TN to San Mateo, CA?

The driving distance from Knoxville, TN to San Mateo, CA is approximately 2,642 miles by road. As the crow flies (straight line), the two cities are 2,114 miles apart.

How long is the drive from Knoxville, TN to San Mateo, CA?

The drive takes about 44 hr 2 min at an average speed of 60 mph. Actual time will depend on traffic, weather, your driving speed, and how often you stop. Plan for additional time on routes with construction, urban congestion, or scenic detours.

How much will gas cost?

For a vehicle averaging 25 MPG, expect to use about 105.7 gallons — roughly $359 at $3.40/gallon. A more efficient vehicle (30 MPG) would use about 88.1 gallons, or $300. Use the calculator above to plug in your own MPG and local gas price.

What's the best route?

The figures above show the most direct driving route. For real-time turn-by-turn directions, current traffic conditions, and to compare alternative routes (interstate vs. scenic), use Google Maps or your preferred GPS app. Toll roads may shave time but add cost — check ahead for E-ZPass / SunPass / FasTrak coverage.

Other distances from Knoxville, TN

Other distances from San Mateo, CA