Distance from Port St. Lucie, FL to Wilmington, NC
Driving directions and distance from Port St. Lucie, FL to Wilmington, NC. See miles, drive time, and estimated gas cost for the trip.
Trip cost calculator
Trip details
| From | Port St. Lucie, Florida (population: 171,016) |
|---|---|
| To | Wilmington, North Carolina (population: 112,067) |
| Driving distance | 627 miles |
| Straight-line (as the crow flies) | 501 miles |
| Estimated drive time | 10 hr 27 min (avg 60 mph) |
| Gas needed at 25 MPG | ~ 25.1 gallons |
| Gas needed at 30 MPG | ~ 20.9 gallons |
| Port St. Lucie coordinates | 27.2730°, -80.3582° |
| Wilmington coordinates | 34.2257°, -77.9447° |
Frequently asked questions
How many miles is it from Port St. Lucie, FL to Wilmington, NC?
The driving distance from Port St. Lucie, FL to Wilmington, NC is approximately 627 miles by road. As the crow flies (straight line), the two cities are 501 miles apart.
How long is the drive from Port St. Lucie, FL to Wilmington, NC?
The drive takes about 10 hr 27 min at an average speed of 60 mph. Actual time will depend on traffic, weather, your driving speed, and how often you stop. Plan for additional time on routes with construction, urban congestion, or scenic detours.
How much will gas cost?
For a vehicle averaging 25 MPG, expect to use about 25.1 gallons — roughly $85 at $3.40/gallon. A more efficient vehicle (30 MPG) would use about 20.9 gallons, or $71. Use the calculator above to plug in your own MPG and local gas price.
What's the best route?
The figures above show the most direct driving route. For real-time turn-by-turn directions, current traffic conditions, and to compare alternative routes (interstate vs. scenic), use Google Maps or your preferred GPS app. Toll roads may shave time but add cost — check ahead for E-ZPass / SunPass / FasTrak coverage.